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Cloning

What is a clone?
A clone is an organism or group of organisms, derived from another organism by an asexual (non-sexual) reproductive process or a group of cells stemming from a single cell.

In general, the members of clones are supposed to be identical except for any differences that occur due to mutations. A number of small organisms known as prokaryotes (for instance, bacteria) and other simple organisms such as most protozoans, some algae, yeasts also reproduce primarily by cloning.

Research has led to the discovery that cloning technique is capable of producing large numbers of genetically identical individuals. This experiment has been successfully carried out on frogs and mice.

   

The biggest breakthrough in successful cloning of an adult mammal was announced in 1997 by a team of Scottish scientists led by Ian Wilmut.

"Dolly"
- the cloned sheep has gone down in history as the most famous farm animal. People all around the world are now seeing the possibility of humans being cloned. After the creation of Dolly, a lot of countries have banned the scientific research on human cloning. Will this incapacitate the future of the scientific research on human cloning?

The question still remains to be divulged - If mammals can be cloned then why not humans? Although it involves an extremely difficult process and has a low accomplishment rate, it might be possible. Meanwhile, the scientists are conducting research on monkeys using a different technique.

Dolly, the sheep - an example of cloning
"Dolly"

 

How was Dolly cloned?
Advances in cloning higher mammals beyond an primitive embryonic stage may be a formidable challenge. Genes in cells at the earliest stages of embryonic life carry the encoded knowledge that instigates cells to develop various parts of the body.

The team of Scottish scientists succeeded in the first live birth of a healthy sheep cloned from an adult mammal. The team scraped skin cells from the donor sheep (sheep A) and these cells were temporarily starved of nutrients to cease cell development. An unfertilized egg was removed from second sheep (sheep B) and its nucleus was removed to eliminate genetic characteristics. A skin cell from sheep A (containing a nucleus with genetic material) was fused with the unfertilized egg, which was got from the sheep B. The egg, now with a nucleus, began dividing and was placed into the uterus of the surrogate mother (sheep C). This embryo developed normally and was delivered safely. This sheep then came into the world in Feb 1997.

It is seen that most of Dolly’s characteristics are that of sheep A (the donor). The creation of Dolly exemplifies a unique advance for the cloning technology, but this has lead to a deep contemplation about human cloning. This technique can also be used for the surgical transplantation of human organs.

What is the future of cloning?
The inescapable question raised- "If other mammals are cloned, why not humans?"
Why are people intimidated by the idea of human cloning? There are various ideas expressed on this issue.

Firstly is human cloning really possible? If it is then why are people so apprehensive about cloning? Why is that we react so strongly against it? We never react negatively when identical twins are born. Here the twins share all their genes while in Dolly’s case it was different. Dolly possesses genes that came not from the parent but from the donor of the egg, which received the nucleus from the "parent". Therefore the conclusion would be that she is not identical to the parent.

Some people have welcomed the idea of cloning wholeheartedly as they see a bright future of the improved farm animals. But it still remains a controversy when it comes to humans - the valid argument being that we could foresee a quick generation of improved farm animals but can we clone useful politicians or leaders to rule the world?

Prohibition of human cloning has already taken place in many countries. But research shows that cloning can be extremely helpful in finding ways to encounter genetically inherited diseases. It could also be a big break through for the development of drugs.

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