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Process Of Metabolism

 
     
 

 

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What Are Anabolism And Catabolism?

If you’re familiar with the process of metabolism, the words anabolism and catabolism will probably not sound foreign to you. For these are the two phases of metabolism. For those of us unfamiliar with metabolism, let us define the word first. Metabolism is the sum of the chemical processes by which cells produce the materials and energy necessary for life. All organisms conduct both anabolism and catabolism constantly. 

Metabolism
Hormones control the direction and rate of metabolism. The rate of metabolism when a person is at rest is called basal metabolic rate. It is the measure of heat produced by metabolism. 

The molecules of glucose and fatty acids or amino acids are involved in the process of metabolism. Our diet is the basic source of the molecules. When digestion takes place in the body, dietary proteins are split into amino acids, dietary fats into fatty acids and dietary carbohydrates into simple sugars such as glucose. The breaking up is caused by enzymes. The compounds produced by the process of splitting are absorbed by the body and transported by the blood to the cells.

Anabolism
Simpler molecules combining to form complex compounds is the process involved in anabolism. Cells combine amino acids to form structural proteins and functional proteins. Structural proteins help repair and replace tissues. Enzymes, antibodies and hormones are functional proteins that respectively catalyze chemical reactions, help fight disease and regulate body processes.

During anabolism, cells convert glucose and fatty acids to energy storage compounds.  For instance, cells in the liver and the muscles combine molecules of glucose to form a storage compound known as glycogen. And cells in the fatty tissues combine with fatty acids with glycerol to form body fat. Body fat can result from a complex series of reactions involving excess glucose and amino acids.

Catabolism
The breaking down of glucose, fatty acids and amino acids for obtaining energy and heat is the process called catabolism. Here the newly digested food, storage glycogen or body protein are the compounds involved. The breaking down of fatty acids takes place into two steps. In the first step, enzymes convert fatty acids into acetyl coenzymes A. In the second step, the Acetyl-CoA enters a series of chemical reactions known as Krebs cycle. 

Similarly, glucose catabolism too goes through two stages. The first step is called glycolysis. Glycolysis  works without oxygen. Glucose is broken down into pyruvic acid. A small amount of energy is also released. If oxygen is present, the pyruvic acid is converted to Acetyl CoA. The second stage then takes place. This is the stage of the Krebs cycle. Here, a series of chemical reactions combines Acetyl-CoA with oxygen to produce carbon dioxide, water and energy.

Energy produced during catabolism
Around sixty per cent of the energy produced during catabolism is heat. The remaining forty per cent is stored in the chemical bonds that link atoms in a compound commonly referred to as ATP (adenosine triphosphate).  When required by the body, the energy stored is broken and released by enzymes.

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